Importantly, there was no evidence for impaired cell viability prior to infection, as equal numbers of myeloid cells were present in BM, spleen and blood of naïve WT and Il23a-/- mice at steady state (S3A–S3C Fig) and these populations did not differ in 7-AAD or Annexin V staining between the two genotypes (S3D and S3E Fig). Here, ANXA5 is linked to infection.