Knockdown of RAPTOR in mice induces spermatogonia self‐renewing disorder, which indicates the cell autonomous requirement for RAPTOR in the formation and maintenance of the spermatogonial stem cell pool and underscores the importance of mTORC1 in male germ cell development.25 Hepatoid adenocarcinoma of stomach (HAS) is characterized by histological resemblance to HCC and has a poor prognosis. This evidence concerns the gene RPTOR and hepatocellular carcinoma.