Moreover, after coculture with autologous DCs, we evaluated the level of IFN-γ secretion by CD4+ T cells challenged with two HLA-A2+ OECCL present in the MOVL1 and MOVL2 lysates (Hey and CAOV3 cells) and HLA-A2+ melanoma cell line (Mel1) or with the leukemic cell line K562 (HLA-DR−) as negative controls. This evidence concerns the gene CD4 and melanoma.