In this context, experimental data demonstrated that cytokine-activated TH1 and TH17 cells foster an increase in hepatic C-X-C motif chemokine 9 (CXCL9) and C-X-C motif chemokine 10 (CXCL10) expression, thereby triggering progression of AIH in mice [49]. Here, CXCL10 is linked to autoimmune hepatitis.