MBP and myeloid sarcoma: The complexes of MHC class II with MBP epitopes have been detected on antigen-presenting cells (APC) in MS lesions [147]; therefore, B cells became involved in the presentation of the epitope in a complement-activated pathway [160], so that the autoantibodies and T cell clones can recognize the immunodominant epitope of MBP in MS patients [161, 162].