Therefore, the study's purpose was to classify wheezing children, who participated in the 2001 study, based on the intensity of their Ascaris infection, total and specific IgEs including anti-Ascaris IgE, parental asthma, and other risk factors to determine the mechanism by which Ascaris causes childhood wheezing in this rural area of Bangladesh and the degree to which it contributes to the development of wheezing. The gene discussed is IGHE; the disease is asthma.