There was no significant correlation between the 3 markers and age, gender, tumor size, histologic grade, or invasive depth, etc. Nonetheless, low-expression of PDIA3 or high expression of ITGA5B1 significantly correlated with lymph node (LN) metastasis, whereas no correlation was found between MYC and LN metastasis (Table 2). Here, PDIA3 is linked to neoplasm.