All the top 10 hub gene were verified by qRT-PCR which presented that AKT1, EGFR, CDC42, FGF2 and MMP2 were significantly decreased in EAT of CAD samples (p < 0.05) and MYC, ACTB, IGF1, CXCR4, and LYN were significantly increased (p < 0.05) (Figure 5). Here, CXCR4 is linked to coronary artery disorder.