Multivariate Cox hazard model analysis of association of these six genes with survival showed that RPS6KL1 and RXFP1 were independent factors associated with good overall survival in NSCLC patients, while RTL1 and RRM2 were independent factors associated with poor overall survival in NSCLC patients (Table 4). This evidence concerns the gene RPS6KL1 and non-small cell lung carcinoma.