NFIL3 and osteosarcoma: Our colony formation assays demonstrated that forced NFIL3 expression in MG-63 and SaOS2 cells promoted cell proliferation compared with the control conditions, whereas NFIL3 knockdown obviously restricted osteosarcoma cell proliferation in these two cell lines compared with the control conditions, as shown in Figure 5(a), and Figure 5(b) is the statistical quantification of Figure 5(a) (P < 0.01).