One patient with chronic hepatitis C showed inhomogeneous, weak expression of ABCB11 and ABCB4, and one FNH patient, accumulation of ABCB4 in some areas, but a homogeneous expression of ABCB11 at the bile canalicular membrane of adjacent hepatocytes (Supplementary  and Supplementary ). Here, ABCB4 is linked to chronic hepatitis C virus infection.