CD8A and Autoimmunity: In the current results, there were many common characteristics of CSF between NMDAR-AE and HSEV patients, including the absolute CSF WBC count, the proportions of CD3 cells and CD8 cells, in spite of the different proportion of CD20 B cells.Previous studies also have showed that the patients with AE may involve B cell-mediated autoimmunity and the proportion of CD19 (+) B cells had been reported to be greater than 10% in CSF, which is significantly higher than that observed in noninflammatory neurological disorders [15].