Cell counting revealed that 75 ± 12.2% of α-SMA-positive fibroblasts in control melanomas expressed nuclear YAP, while only 24.17 ± 17.4% α-SMA-positive fibroblasts in BrafV600E; Ptenlox5-bcat/Fb melanomas possessed nuclear YAP (Fig. 4q). The gene discussed is ACTA1; the disease is melanoma.