By flow cytometry, we observed that hiPSC-RPE Control and AMD cells mainly die by apoptosis during Fe-NTA exposure (43% ± 4.8 and 62.9% ± 4.6 of annexin-V-positive cells, respectively); less than 10% of cells showed necrotic marker PI staining (Figures 5(d) and 5(e)). This evidence concerns the gene ANXA5 and age-related macular degeneration.