APOA5 and metabolic dysfunction-associated steatotic liver disease: From this search, there were identified some targets that had their expression modulated by NAFLD and/or GT in an inverse manner to their respective miRNA, the selected genes were Sirt1, Pparα, and Insig2 for miR-34a; Apoa5 and Hmgcs2 for miR-194 (Figure 4(c)).