They found that abnormal cardiac relaxation can be positively correlated with high levels of MMP-2 in patients with cardiac dilation occurring due to cardiomyopathy and then suggested that the MMPs 2 and 9 may act as potential biomarkers that can be used to identify not only the advent of cardiomyopathy but also its occurrence and progression in individuals infected with T. cruzi. The gene discussed is MMP2; the disease is cardiomyopathy.