YPFS has a certain effect on Th2-type cytokines such as (IL-4, IL-6, IL-10, and IL-17) and Th1 type cytokines such as (IFN-γ and tumor necrosis factor-α), and YPFS mainly exerts pharmacological effects such as immune regulation and anti-allergy and anti-inflammatory by acting on these cytokines. This evidence concerns the gene IL4 and allergic disease.