We analyzed the significance among normal and tumor tissues, and we found that only OCT4 (p value < 0.0001) and SOX2 (p value = 0.0014) had higher expression in tumor tissues, not so for KLF4 (p value = 0.0610), C-MYC (p value = 0.0900), or NANOG (p value = 0.0969). This evidence concerns the gene KLF4 and neoplasm.