The AARS2‐related ALSP patient shared the same AARS2 pathogenic variant with a Turkey middle‐aged patient who presented a rapid progression and died in 1 year after symptoms onset.15 But there were no evident dystonia, dysarthria, cognitive deterioration, or neuropsychiatric symptoms in our patient as the Turkey patient presented.15 The two CSF1R‐related ALSP patients showed great clinical heterogeneity, especially in the patients with CSF1R c.2381T>C. The gene discussed is CSF1R; the disease is Dystonia.