CALCA and infection: At 5 h after infection Cfh−/− mice had significantly lower brain levels of interleukin (IL)-1β (0.13 vs. 0.30 ng/mg tissue, P = 0.013), IL-6 (0.32 vs. 0.86 ng/mg tissue, P = 0.035), macrophage inflammatory protein 2 (MIP-2) (0.61 vs. 1.93 ng/mg tissue, P = 0.009) and keratinocyte chemoattractant (KC) (0.71 vs. 1.11 ng/mg tissue, P = 0.044) compared to wt mice.