It has been reported that overexpression TPX2 can suppress cell proliferation and invasion and can predict a poor survival in BCa.29, 30 Non–structural maintenance of chromosomes condensin I complex subunit G (NCAPG) can active the condensin complex to promote the meiosis and mitosis.31 Most of previous publications proved that NCAPG can affect cell proliferation and invasion in prostate cancer and hepatocellular carcinoma. Here, TPX2 is linked to prostate cancer.