As listed in Table 1, a significant correlation was found between the depth of invasion (T) (P = .042) and Ki67 expression (P = .003), while B7H5 expression in the cytoplasm was not significantly associated with age, sex, lymph node metastasis (N), distant metastasis (M), TNM stage, p53 expression or pathological grade. This evidence concerns the gene MKI67 and metastatic malignant neoplasm in the lymph nodes.