20 He et al. showed that inhibition expression of ALCAM repressed proliferation and invasion of pituitary adenomas cells.21 Moreover, Ishiguro and his colleagues revealed that knockdown of ALCAM suppressed NSCLC cell migration and invasion and that it was associated with the prognosis of NSCLC patients.22 Based on these studies, we further investigated the effect of ALCAM on miR‐148b in regulating NSCLC invasion and migration. This evidence concerns the gene ALCAM and pituitary gland adenoma.