Nuclear factor κB (NF‐κB) is a nuclear transcription factor which regulates expression of a large number of genes critical for the regulation of apoptosis, tumorigenesis, inflammation, and various autoimmune diseases.23, 24, 25 The NF‐κB signaling pathway is modulated by several miRNAs in certain types of cancers as previously reported.26, 27 Thus, we examined whether the NF‐κB signaling pathway was regulated by miR‐148b in NSCLC. The gene discussed is NFKB1; the disease is autoimmune disease.