To verify whether ALCAM was the direct target of miR‐148b, miR‐148b mimic or inhibitor was transfected into two NSCLC cells and the results indicated that miR‐148b restoration significantly reduced ALCAM mRNA and protein levels, while increased with miR‐148b inhibitor (Fig 3b,c). This evidence concerns the gene ALCAM and non-small cell lung carcinoma.