PRDM1 and HIV infectious disease: Similar to Batf, Blimp‐1 is upregulated in progressor patients with chronic HIV infection compared to non‐progressors that control HIV viral loads.33 Blimp‐1 expression in CD4 T cells mediates the production of IL‐10, which can further contribute to the dysfunctional state of exhausted T cells during chronic viral infection.34 Exhausted T cells may coexpression pairs of transcription factors including Blimp‐1 and Eomes, however, expression is not uniform where combinations of different factors may coexist.