Increasing the administered antibody dose to 30 μg decreased the splenic uptake from 14.44 ± 3.10 to 5.59 ± 0.51 %ID/g and concurrently allowed visualisation of tumour PD-L1 by increasing the tumour uptake ~ 5-fold from 0.35 ± 0.04 to 1.72 ± 0.24 %ID/g. The gene discussed is CD274; the disease is neoplasm.