Adolescent prenatally androgenised ovine males had increased circulating concentrations of total cholesterol, HDL-C, LDL-C, TG, AMH and insulin, independent of body weight, adiposity and contemporary testosterone concentrations, thus faithfully reproducing the dyslipidaemic / endocrine profile of first degree male relatives of PCOS patients26–30. This evidence concerns the gene INS and polycystic ovary syndrome.