However, in this study, we demonstrated that the lysates alone partially reversed the dysregulation of homeostasis in the fecal microbial community induced by AOM/DSS treatment in BALB/c mice, significantly increased the CD8 + CD62L+ T cells in mLN of CRC mice, and did not affect TNF-a and IL-10 expression levels. This evidence concerns the gene IL10 and infectious otitis media.