However, there is a paucity of data regarding the activity of EGFR-TKIs in NSCLC harbor uncommon EGFR mutations, such as G719X, L861Q, S768I alone or in combination with each other, which occur in approximately 10% of EGFR-mutant NSCLC31. The gene discussed is EGFR; the disease is non-small cell lung carcinoma.