Consistent with our hypothesis, the number of CD14dimCD16+ non-classical monocytes were significantly lower in both statin-treated cohorts compared to SIV-PAH+ controls (Fig. 4a; SIV/Statin Group 2, P = 0.02; SIV/Statin Group 3, P = 0.005) and did not correlate with increased pulmonary pressures (Fig. 4b, center, right panels). This evidence concerns the gene EEF1A2 and pulmonary arterial hypertension.