Moreover, the numbers of BALF CD14+CCR7−CD163−CD206+ BALF macrophages were significantly reduced with statin treatment (Fig. 4c; SIV/Statin Group 2, P < 0.0001; SIV/Statin Group 3, P < 0.0001) compared to both SIV-PAH+ and SIV-PAH− controls. This evidence concerns the gene CD14 and pulmonary arterial hypertension.