They harboured the recently described pathogenic homozygous p.S208C mutation in MEFV. This gene is mutated in patients with familial Mediterranean fever (FMF) and pyrin-associated autoinflammation with neutrophilic dermatosis (PAAND) (Masters et al, 2016; Moghaddas et al, 2017). Here, MEFV is linked to familial Mediterranean fever.