Specifcally, MMPs selectively degrade different components of the ECM8 and thus regulate numerous biological events, including cell growth, inflammation, invasion, and angiogenesis by eliminating cell surface proteins such as the cytokine receptor, cell adhesion molecules, and urokinase receptors.5, 9, 10 Among all MMP members,MMP-2 and MMP-9 have been reported to correlate with tumor metastasis.11, 12. The gene discussed is MMP9; the disease is neoplasm.