PAX8 silencing can significantly cause the silencing of Aurora B and Cyclin B1, the expression of Aurora B and Cyclin B1 were recovered, when PAX8 was expressed in AGS and MGC803 cells, confirming that PAX8 can regulate the expression of Aurora B and Cyclin B1 in stomach cancer (Fig. 3g). Here, CCNB1 is linked to gastric neoplasm.