To explore the differences of PAX8 and SOX13 expression pattern in different stomach cancer cell lines, SOX13 was found to significantly up-regulated in stomach cancer cell lines as the expression pattern of PAX8, especially in MGC803 and AGS cell lines, by comparing PAX8 and SOX13 expressed in 4 stomach cancer cell lines with GES1 cells (Fig. 1g, h). The gene discussed is PAX8; the disease is gastric neoplasm.