More interestingly, in CRC patients at AJCC stage III-IV, higher AGGF1 expression was significantly associated with poorer OS (p = 0.001, Fig. 2d), while no significant difference between higher and lower AGGF1 expression was observed for OS in patients at AJCC stage I- II, (p = 0.2248, Fig. 2c). The gene discussed is AGGF1; the disease is colorectal carcinoma.