For example, in normal kidney FGFR2-IIIb is overexpressed in detriment of FGFR2-IIIc, while in clear cell renal cell carcinoma (ccRCC), FGFR2-IIIc becomes overexpressed in detriment of FGFR2-IIIb [39]. Here, FGFR2 is linked to clear cell renal carcinoma.