In this network gene such as TAOK1, ZNF708 and ZNF101 along with miRNA such as hsa-mir-3941, hsa-mir-1183, hsa-mir-6832-5p, hsa-mir-4662b and hsa-mir-3187-3p were predicted as novel prognostic or diagnostic biomarkers and new therapeutic target in CAD. This evidence concerns the gene TAOK1 and coronary artery disorder.