ITGAX and amyloidosis: In these pathways genes such as CYP2E1, A2M, coagulation factor II (thrombin) (F2), complement factor I (CFI), SERPINC1, integrin, alpha X (complement component 3 receptor 4 subunit) (ITGAX), complement factor B (CFB), C1S, C4BPA, KNG1, transthyretin (prealbumin, amyloidosis type I) (TTR) aldolase B, fructose-bisphosphate (ALDOB), G6PC, MT1B, MT1E, MT1F, MT1G, MT1H, MT1M, MT1X, ADH1A, ADH4 and ACAA2 were predicted as novel prognostic or diagnostic biomarkers and new therapeutic targets in CAD.