ABCG2 and Wolman disease: In pathway enrichment analysis, up regulated genes were enriched in various pathway databases such as superpathway of steroid hormone biosynthesis, ABC transporters, BARD1 signaling events, ABC-family proteins mediated transport, methionine metabolism, telomeres, telomerase, cellular aging, and immortality, androgen/estrogene/progesterone biosynthesis, multidrug resistance-associated protein mediated transport and lysosomal acid lipase deficiency (Wolman Disease).