In these GO categories genes such as alpha-2-HS-glycoprotein (AHSG), histidine-rich glycoprotein (HRG), FN1, ORM1, ORM2, TMPRSS13, ACTG1, haptoglobin-related protein (HPR), alpha-1-microglobulin/bikunin precursor (AMBP), APOA2, group-specific component (GC), ITIH1, ITIH2, acrosin binding protein (ACRBP) and PEBP1 were predicted as novel prognostic or diagnostic biomarkers and new therapeutic target in CAD. This evidence concerns the gene ITIH1 and coronary artery disorder.