In these pathways genes such as HSD17B11, ABCB4, ABCC2, ABCA6, FANCD2, UBE2D3, NPM1, PSMA3, methionyl-tRNA synthetase (MARS), 5-methyltetrahydrofolate-homocysteine methyltransferase (MTR), v-myc myelocytomatosis viral oncogene homolog (avian) (MYC) and TERF1 were predicted as novel prognostic or diagnostic biomarkers and new therapeutic target in CAD. This evidence concerns the gene FANCD2 and coronary artery disorder.