Univariate and multivariate analysis of biomarker expression in the treatment-naïve glioma cohort showed significantly lower values for vimentin (p = 0.0002), VEGFR2 (p = 0.0002), nestin (p = 0.003), Ki67 (p = 0.006) and HLA1 (p = 0.008) proteins in IDHmt vs wt tumors (S6A Fig). The gene discussed is KDR; the disease is central nervous system cancer.