Our in vitro results confirm that AMSCs exposed to high concentrations of insulin, glucose and palmitic acid, simulating the hyperinsulinemia, hyperglycemia, and dyslipidemia observed in metabolic syndrome40 but also in pregnancies complicated by diabetes,41 reproduced the inflammatory expression profile, the migration capacity, and the chemotactic activity observed in GDM‐derived AMSCs. Here, INS is linked to diabetes mellitus.