Moreover, a significant elevation of miR‐211‐5p was observed in HBV− HepG2 and HBV− Huh7 cells following transfection with pHBV1.3 (*P < .05) (Figure 4D), suggesting the inhibition of lncRNA F11‐AS1 caused by HBx protein might affect miR‐211‐5p expression in HCC. This evidence concerns the gene F11 and hepatocellular carcinoma.