SLAMF9 and experimental autoimmune encephalomyelitis: However, Sever et al. also reported a relative decrease in the frequency of TNF‐α‐producing pDCs in CpG‐stimulated lymph node cells from Slamf9−/− mice with experimental autoimmune encephalomyelitis.30 If optimal TNF‐α production is dependent on SLAMF9 expression across multiple cell types, this may help to explain the impaired clearance of Salmonella in our studies.