Similar to the findings of Koduri et al we did not observe many cases of severe anaemia and hemoglobin levels increased after discontinuation of zidovudine.18 Huffam et al, found that young female HIV patients with low baseline hemoglobin (Hb <10 g/dl) were at higher risk of zidovudine-induced anemia.20 A highly significant association (OR: 61.65, P <0.0001) was also revealed between the use of zidovudine and the occurrence of anemia, as previously reported.17 However, in this study, young age and female gender were not significantly associated with anemia. Here, GSTM1 is linked to anemia (phenotype).