For ovarian serous cystadenocarcinoma, there was a total of 12 (MME, AGTR1, SOX17, PTN, NTF3, MSR1, PGR, PLCB1, BNC2, PTGIS, LEP, and PAX8) genes with >4% of genetic alterations frequency. The gene discussed is PGR; the disease is ovarian serous cystadenocarcinoma.