As extensively studied in relation to cancer, Mortalin is overexpressed in a variety of tumors, including breast, pancreatic, lung, and ovarian cancers, and it is associated with multiple processes of carcinogenesis, which include the inactivation of tumor suppressor p53, deregulation of apoptosis, activation of EMT, and induction of cancer cell stemness. This evidence concerns the gene HSPA9 and ovarian cancer.