In addition to the finding that the CDC transcriptome is unique and clustered with that of clear cell renal cell carcinoma (ccRCC) patients rather than UTUC patients, the authors compared CDCs with UTUCs and identified CDH6 and POU3F3 as the top upregulated genes and GATA3, TP63, KRT17, KRT7, KRT20, UPK2, UPK1A, and UPK3A as the top downregulated genes in CDCs [6]. Here, KRT17 is linked to nonpapillary renal cell carcinoma.