Moreover, tumors cultured from NK-injected tumor-bearing hu-BLT mice contained about 18–22 fold more huCD45+ immune cells and secreted higher IFN-γ in the presence of lower IL-6 secretion, whereas those cultured from tumor-bearing mice in the absence of NK injection had lower infiltrating huCD45+ cells and secreted lower IFN-γ in the presence of much higher IL-6 secretion. This evidence concerns the gene IFNG and neoplasm.