ITGAM and neoplasm: Our findings also revealed an increase in the percentage of CD11b+Ly6G+Ly6C+ granulocytes (or PMN-MDSCs) and CD11b+Ly6G−Ly6C+ monocytes (or M-MDSCs) after DT injections (Figure 1D), but not in tumor-bearing CD11b-DTR mice (Figure 3D).