MRP4 and MRP5 have been detected in human astrocytes, while MRP5 has also been observed in human pyramidal neurons [46] and astrocytes [15], as well as primary cultures of rat astrocytes [123] and microglia [47,124]; nevertheless, these experiments were performed in samples from patients with epilepsy or glioma, and the expression may be tuned by the disease. The gene discussed is ABCC5; the disease is central nervous system cancer.