APOA1 and ischemic stroke: Ning et al. reported that miR-124 was at least partially contributing to the apolipoprotein-A1 mimetic peptide, D-4F, induced M2 macrophage polarization and anti-inflammatory effects in type one diabetes mellitus (T1DM) ischemic stroke rats, reducing the expression of inflammatory factors in the ischemic brain, and improving neurological functional outcomes after ischemic stroke [72].