WB analysis of the appendages lysates indicated that the expression of p53 and p16 were significantly increased in the AF group compared with the SR group (0.91 ± 0.31 vs. 0.58 ± 0.31, p = 0.001 and 0.76 ± 0.32 vs. 0.35 ± 0.18, p = 0.0001) as well as that of TF, the main cellular activator of the blood coagulation (AF: 0.88 ± 0.32 vs. SR: 0.68 ± 0.29, p = 0.045) (Figure 1). The gene discussed is TP53; the disease is atrial fibrillation.