CYP24A1 and Wilson disease: In ascending colons of the WD group, the expression of Cyp24a1 was 18.7-fold (Figure 4C, p < 0.001) and 8.8-fold (Figure 4C, p < 0.001) higher when compared with the AIN group and the WD/AIN group, respectively, although the Vdr mRNA level did not change significantly (Table S3), similar to Cyp27b1 or Casr expression (Table S3).