IDH2 and diffuse astrocytoma: The distribution of LGGs according to the 2016 WHO classification of brain tumors [4] was diffuse astrocytomas, IDH-mutant (astrocytomas IDHmt), oligodendrogliomas, IDH-mutant, and 1p/19q-codeleted (oligodendrogliomas), and diffuse astrocytoma, IDH-wildtype (astrocytomas IDHwt) in 56.8%, 32.0%, and 11.2%, of cases, respectively.